Left Ventricular Diastolic Dysfunction in Pediatric Pulmonary Hypertension

Left Ventricular Diastolic Dysfunction in Pediatric Pulmonary Hypertension.

Pulmonary hypertensive vascular disease (PHVD) is characterized by progressive narrowing of pulmonary arterioles, abnormally high pulmonary vascular resistance (PVR), right ventricular (RV) dysfunction, left ventricular (LV) compression, and death in ≈25% to 60% of patients with pulmonary arterial hypertension (PAH) 5 years after diagnosis. Meanwhile, consensus statements have been developed in...

Abnormal left ventricular diastolic filling in chronic thromboembolic pulmonary hypertension: true diastolic dysfunction or left ventricular underfilling?

OBJECTIVES The purpose of this study was to investigate the cause of abnormal left ventricular (LV) Doppler diastolic filling characteristics in chronic thromboembolic pulmonary hypertension (CTEPH). BACKGROUND In CTEPH, LV diastolic function often appears abnormal. It is unclear whether this "impaired relaxation" (E<A) filling pattern is caused by septal hypertrophy, right ventricular (RV) e...

Prognostic significance of left ventricular diastolic dysfunction in essential hypertension.

OBJECTIVES We sought to assess the prognostic value of alterations in left ventricular (LV) diastolic function in patients with essential hypertension. BACKGROUND Alterations in LV diastolic function are frequent in patients with hypertension, even in the absence of LV hypertrophy, but their prognostic significance has never been investigated. METHODS In the setting of the Progetto Ipertens...

Maternal diastolic dysfunction and left ventricular geometry in gestational hypertension.

The objective of this study was to evaluate diastolic parameters and left ventricular geometry in gestational hypertension. Twenty-one consecutive pregnant women with gestational hypertension and 21 normotensive women matched for age and gestational age were enrolled in the third trimester of gestation. Echocardiographic and uterine color Doppler evaluations were performed. Systolic, diastolic,...

P-wave dispersion and left ventricular diastolic dysfunction in hypertension